The Electronic Medical Records and GEnomics (eMERGE) Network Genomic Risk Assessment
Status: Active_not_recruiting
Location: See all (12) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The eMERGE Network embraces the opportunity to use new methods in genomic medicine, information science, and research participant engagement to identify people at very high risk for specific diseases and recommend individualized approaches to prevention and care. The investigators will conduct a prospective study, with diverse and underserved participants, across ten eMERGE study sites to evaluate clinical implementation of a Genome Informed Risk Assessment (GIRA) tool that combines genetic, family history, and clinical risk information from participants.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 75
Healthy Volunteers: t
View:
• Adults 18-75
• Children 3 to \< 18
• Able to read or understand English or Spanish
• Able to provide a healthcare provider or clinician to receive results
• Willing to accept GIRA report
Locations
United States
Alabama
University of Alabama Birmingham
Birmingham
Arizona
Mountain Park Health Center
Tempe
Illinois
Northwestern
Chicago
Massachusetts
Brigham and Women's Hospital
Boston
Massachusetts General Hospital
Boston
Minnesota
Mayo Clinic
Rochester
New York
Columbia University
New York
Mount Sinai
New York
Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati
Pennsylvania
Children's Hospital of Philadelphia
Philadelphia
Tennessee
Vanderbilt University Medical Center
Nashville
Washington
University of Washington
Seattle
Time Frame
Start Date: 2022-02-16
Completion Date: 2026-12-01
Participants
Target number of participants: 26877
Treatments
Experimental: Participants receiving a Genome Informed Risk Assessment (GIRA)
All participants and their health care providers will receive a Genome Informed Risk Assessment (GIRA) report.
Authors
Sponsors
Leads: Vanderbilt University Medical Center