Advances of mesenchymal stem cells transplantation for treating intervertebral disc degeneration

Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal Of Reparative And Reconstructive Surgery
Published:
Abstract

Objective: To introduce the research of mesenchymal stem cells(MSCs) transplantation for treating intervertebral disc degeneration.

Methods: The recent original articles about the MSCs transplantation for treating intervertebral disc degeneration were extensively reviewed.

Results: Transplanted MSCs in intervertebral disc can express chrondcyte-like phenotype in certain conditions, increase matrix synthesis and release intervertebral disc degeneration.

Conclusions: MSCs transplantation for treating intervertebral disc degeneration may be a future approach.

Authors
Tao Liang, Hao Liu