Solitary fibrous tumor with pseudo-lipoblasts involving the sublingual gland: report of a case and review of the literature.

Journal: European Archives Of Oto-Rhino-Laryngology : Official Journal Of The European Federation Of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated With The German Society For Oto-Rhino-Laryngology - Head And Neck Surgery
Published:
Abstract

Solitary fibrous tumors (SFTs) are mesenchymal neoplasms uncommonly occurring in the salivary glands. In rare instances, SFTs can contain mature fat, atrophic fat, or vacuolated cells previously termed 'pseudo-lipoblasts', which may be misinterpreted as a feature of malignancy. We report an unusual tumor with pseudo-lipoblasts occurring in the sublingual gland. The tumor exhibited a prominent hemangiopericytic pattern, bland cytology, and immunohistochemical and morphologic features consistent with that of an SFT. A review of 15 cases of SFTs of the salivary glands is presented. Emphasis is laid upon the histologic differential diagnosis and the clinical features of these tumors.

Authors
Tareck Ayad, Julien Ghannoum