A rare gynecological case of paraneoplastic cerebellar degeneration discovered by FDG-PET.

Journal: Gynecologic Oncology
Published:
Abstract

Background: PET/CT may be particularly useful to detect the primary cancer in paraneoplastic cerebellar degeneration (PCD) with anti-Yo which is most commonly associated with breast, ovarian and other gynecological cancers.

Methods: A 60-year-old woman developed a PCD associated with anti-Yo antibodies in serum and cerebrospinal fluid. Conventional imaging was negative. FDG-PET showed an abnormal hot spot in the right ovarian area associated with lombo aortic lymph nodes. The diagnosis was confirmed by surgery as an ovarian adenocarcinoma.

Conclusions: In this case report, FDG-PET played a crucial role in detecting the unknown primary tumor in a patient with PCD.

Authors
V Marchand, J Graveleau, C Lanctin Garcia, E Bourbouloux, B Bridji, I Resche, F Kraeber Bodéré, C Rousseau