Castleman's disease of the cervical region: a case report

Castleman's disease is a rare disorder characterized by massive proliferation of the lymphoid tissue due to an unknown cause. Two clinical types (localized, multicentric) have been described with three histological variants (hyaline-vascular, plasma cell, and mixed type). A 47-year-old female patient was referred to our department because of a swelling in the posterior cervical region. Fine-needle aspiration biopsy was suggestive of lymphoma. Total excision of the mass was performed under general anesthesia with intraoperative frozen section examination. Histopathologic diagnosis was Castleman's disease of hyaline-vascular type. Castleman's disease should also be considered for suspicious masses in the neck.