Different fundus autofluorescence patterns of retinoschisis and macular hole retinal detachment in high myopia.

Objective: To report difference in fundus autofluorescence (FAF) results between macular hole retinal detachment (MHRD) and myopic foveoschisis (MF) in highly myopic eyes.

Methods: Observational case reports. Methods: Total of 20 highly myopic eyes were included in this study (MHRD, six eyes; MF with macular hole [MH], three eyes; MF without MH, 11 eyes). The authors observed both standard and near-infrared FAF images using the Heidelberg Retina Angiograph 2 (HRA2; Heidelberg Engineering, Heidelberg, Germany).

Results: MHRD typically showed extensive hypo-FAF and foveal hyper-FAF. Hypo-FAF and hyper-FAF seemed to account for RD area and MH, respectively. Some cases of MF had almost normal results, except for a subtle mottled pattern of hyper-FAF.

Conclusions: MHRD and MF showed different patterns of FAF, and this fact could be helpful in diagnosing MHRD from MF. Hyperviscous subretinal fluid might have blocked FAF signal in MHRD, but not in MF.