Synthesis and fluorescence properties of oligonucleotides containing pyrene-dimethylaniline chromophore.

The photophysical properties of DNA oligomers containing novel uracil derivatives tethering a solvatochromic pyrene-dimethylaniline (Py-DMA) chromophore were investigated. In the steady-state fluorescence measurements of the modified DNA oligomer, dual fluorescence, originating from a locally excited (LE) and a twisted intramolecular charge transfer (TICT) state, was observed.