Respiratory syncytial virus infection and recurrent wheezing: what next?

Recent literature has provided evidence of a link between early RSV infection and chronic respiratory morbidity (recurrent wheezing, reactive airway disease and asthma). The mechanism of this association is not well understood but both genetic and environmental factors are involved. The classical studies from Sweden, Tucson and Finland are briefly summarized. Moreover new data concerning a recent multi-center international study on this topic are presented. The study, which enrolled 191 preterm infants (