POEMS syndrome: relapse after successful autologous peripheral blood stem cell transplantation.

Journal: Neuromuscular Disorders : NMD
Published:
Abstract

We report a patient with POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) treated with high dose chemotherapy and auto-Peripheral Blood Stem Cell Transplantation (auto-PBSCT) who had a very good response with complete clinical remission. Seven years later, she relapsed and a new sclerotic bone lesion was found. To our knowledge, this is the first POEMS syndrome relapse after successful auto-PBSCT.

Authors
F Giglia, L Chiapparini, L Fariselli, T Barbui, C Ciano, M Scarlato, D Pareyson