C-H bond functionalization in the synthesis of fused 1,2,3-triazoles.

Journal: Organic Letters
Published:
Abstract

A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.

Authors
Jane Panteleev, Karolin Geyer, Angelica Aguilar, Letian Wang, Mark Lautens