A case of recurrence after curative total gastrectomy for gastric cancer successfully treated by combination chemotherapy with CPT-11 and CDDP

A male in his sixties underwent total gastrectomy for gastric cancer in August, 2002. After surgery, he underwent 4 courses of adjuvant chemotherapy with S-1. About 2 years after the surgery, PET-CT detected liver metastasis and lymph node metastasis, so treatment with CPT-11+CDDP was started with the following regimen: 60 mg/m2 CPT-11 and 30 mg/m2 CDDP biweekly. Five months later, PET-CT revealed that the liver metastasis and lymph node metastasis had disappeared. After judgment of complete response(CR), we continued that treatment every four weeks for one year and every eight weeks for another one year. The patient was followed without any recurrence in January, 2007. For this case, PET-CT was effective for planning the treatment and assessing its response.