Specific serum agglutination of erythrocytes sensitized with extracts of tubercle bacilli.

Journal: The Journal Of Experimental Medicine
Published:
Abstract

A hemagglutination reaction has been described between sheep erythrocytes treated with a component of a polysaccharide fraction of mammalian tubercle bacilli and the sera of experimental animals or of tuberculous patients. Evidence has been presented for the specificity of this reaction. A modification of the test, involving an inhibition reaction, has been developed for the detection and quantitation of minute amounts of the material responsible for the hemagglutination reaction.

Authors
G Middlebrook, R Dubos