Laparoscopic ovarian transposition before pelvic irradiation: a Saudi tertiary center experience.
Objective: To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy.
Methods: Cohort study. Methods: The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia. Methods: Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy. Methods: Laparoscopic ovarian transposition to paracolic gutters with uterine conservation. Methods: Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level.
Results: Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up.
Conclusions: Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.