A case of idiopathic pulmonary alveolar proteinosis with multiple localized ground-glass opacities

Journal: Arerugi = [Allergy]
Published:
Abstract

A 58-year-old Japanese female consulted our staff with multiple localized ground-glass opacities in chest CT. She underwent video assisted thoracoscopic surgery for diagnosis. Histopathologic finding from surgery specimen in one of ground-glass opacities revealed bronchioloalveolar carcinoma. Six months later, we performed second video assisted thoracoscopic surgery, and histopathologic finding of all other ground-glass opacities revealed pulmonary alveolar proteinosis. Serum anti GM-CSF antibody elevated, and she was diagnosed as having idiopathic pulmonary alveolar proteinosis. A case of idiopathic pulmonary alveolar proteinosis presenting multiple localized ground-glass opacities is rare. And, differentiating ground-glass opacities of pulmonary alveolar proteinosis and bronchioloalveolar carcinoma by chest CT is difficult.

Authors
Hirokazu Taniguchi, Hitoshi Abo, Masayoshi Touge, Hideki Shinnou, Hideki Miyazawa, Hirofumi Noto, Akio Uchiyama, Atsuo Miwa, Shoetsu Shimura, Saburo Izumi