Quantitative assessment of anterior chamber volume using slit-lamp OCT and Pentacam.

Objective: To quantitatively assess and compare the anterior chamber volume (ACV) by different anterior segment imaging techniques.

Methods: Forty healthy eyes of 40 patients were recruited and three consecutive measurements of ACV were determined prospectively utilizing SL-OCT and Pentacam. Statistical significance of interdevice differences between measurements was evaluated by unpaired t test and Bland-Altman analysis. The repeatability of three consecutive measurements was analyzed by repeated measured analysis of variance.

Results: Eighty eyes of 40 patients (18 female, 22 male) with a mean spherical error of -0.55+/-1.4 diopters were included in the study. Mean ACV were detected as 163.34+/-29.76 mm3 by Pentacam and 164.14+/-28.44 mm3 by SL-OCT (unpaired t test, p=0.872). Pentacam and SL-OCT displayed a high intrasession repeatability (repeated measured analysis of variance, p>0.05). ACV values detected by SL-OCT were clinically interchangeable with Pentacam.

Conclusions: Noncontact measurements of ACV using SL-OCT and Pentacam were easy to handle and demonstrated good repeatability. The tested devices were regarded as compatible in measuring ACV.