Prospective randomized trial of TVT and TOT as primary treatment for female stress urinary incontinence with or without pelvic organ prolapse in Southeast China.

Objective: To compare the outcomes of tension- free vaginal tape (TVT) and transobturator tape (TOT) in the treatment of female stress urinary incontinence with or without concomitant pelvic organ prolapse (POP).

Methods: One hundred and forty patients with SUI were randomly allocated to TVT (n=70) or TOT (n=70). The objective outcomes were assessed with a stress test, 1-h pad test. Subjective outcomes were assessed with UDI-6/(IIQ-7) questionnaires.

Results: The surgical outcomes revealed no significant difference between TVT and TOT surgical route. Both the subjective and objective cure rates were 91.4% in the TOT group, while 90 and 92.8% in the TVT group, respectively. The results showed the association to pelvic floor surgical techniques did not diminish a year later. TOT procedure has a shorter operative time for patients without concomitant surgery.

Conclusions: The efficacy and safety of TVT procedure were similar to that of TOT procedure for female stress urinary incontinence with or without concomitant POP.