Study on the release of oleanolic acid loaded nanocapsules in vitro
Journal: Zhong Yao Cai = Zhongyaocai = Journal Of Chinese Medicinal Materials
Published:
Abstract
Objective: To study the release of oleanolic acid loaded nanocapsules in vitro.
Methods: The rules of drug release in vitro from oleanolic acid loaded nanocapsules were observed by dynamic penetration system and HPLC.
Results: The profile curve of oleanolic acid loaded nanocapsules was fit for the Weibull equation. The release t(1/2) of oleanolic acid loaded nanocapsules was about 6.7 times as that of original oleanolic acid.
Conclusions: Oleanolic acid loaded nanocapsules have obviously sustained effect.
Authors
Yi Huang, Yuan Li, Xin-zhong Li, Shao Liu, Peng Lei, Jin Xiao