Primary cervical tracheal monophasic synovial sarcoma confirmed by SYT-SSX gene rearrangement.

Objective: To review the existing diagnostic modalities and treatment for primary tracheal synovial sarcoma, and to report a case of primary cervical synovial sarcoma arising in the trachea.

Methods: Retrospective. Methods: Head and neck surgery unit at a tertiary university centre. Methods: One case of primary cervical tracheal monophasic synovial sarcoma diagnosed by SYT-SSX gene rearrangement. Methods: This patient underwent surgical resection of the synovial sarcoma, together with tracheal resection and primary anastomosis assisted by laryngeal-releasing manoeuvres, without complication. Methods: Clinical, radiographical, pathological and surgical information were collected.

Results: One year post-operatively, there was no evidence of recurrence.

Conclusions: Synovial sarcoma arising in the trachea is very rare. Diagnosis is confirmed by demonstrating the SYT-SSX gene rearrangement. The first-line treatment is surgery.