Follow-up CT and MR findings of osteoblastic spinal metastatic lesions after stereotactic radiotherapy.

Objective: We retrospectively analyzed pre and post-stereotactic radiotherapy CT and MRI findings and volume changes for osteoblastic spinal metastatic lesions.

Methods: Of 114 lesions in 72 patients, 11 were osteoblastic. CT and MR images were reviewed to determine tumor volume, CT attenuation, T2 signal intensities, and contrast enhancement.

Results: Tumor volume did not change for 10 lesions and increased for 1 lesion. CT attenuation increased for 8 lesions with heterogeneous T2 signal intensities. Of these 8 lesions, 4 had patterns of dark signal foci and the other 4 had patterns of both dark and bright signal foci. T2 signal intensity became heterogenous, with dark and bright foci, for 2 of 3 lesions for which CT attenuation decreased, and normalized for the third lesion. The degree of contrast enhancement decreased for 6 lesions and did not change for 5 lesions.

Conclusions: There were no changes in volume except for one case. On CT images, sclerotic changes were more common than loss of sclerotic foci. On T2-weighted images, dark signal intensities with or without bright signal foci developed and the degree of enhancement decreased for more than half of the cases.