The clinical characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis.
Journal: Internal Medicine (Tokyo, Japan)
Published:
Abstract
We herein report the clinical and laboratory characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis (PM/DM). We compared these characteristics with previously published findings. Previous reports and our present cases show that anti-OJ autoantibody-positive interstitial lung disease (ILD) patients with PM/DM lack the manifestations of Raynaud's phenomenon and sclerodactyly and show good prognoses and responses to glucocorticoid therapy. These results indicate that the presence of anti-OJ autoantibodies may be useful for predicting the prognosis of ILD and its clinical course in PM/DM patients.
Authors
Kei Kunimasa, Machiko Arita, Takashi Nakazawa, Maki Tanaka, Kazuya Tsubouchi, Satoshi Konishi, Yasushi Fukuda, Mika Saigusa, Hiroaki Nakagawa, Satoshi Ubukata, Yohei Korogi, Takao Fujii, Tsuneyo Mimori, Tadashi Ishida
Relevant Conditions