A case of synchronous multiple liver metastasis of sigmoid colon cancer with a pathological complete response to combination chemotherapy of 5-FU/LV and bevacizumab
Journal: Gan To Kagaku Ryoho. Cancer & Chemotherapy
Published:
Abstract
A 73-year-old man was referred to our hospital with sigmoid colon cancer in July 2009. CT and MRI showed synchronous multiple liver metastasis. After a sigmoid colon resection in August, he received convergent chemotherapy in combination with 5-fluorouracil(5-FU)/Leucovorin(LV)(RPMI regimen)and bevacizumab for liver metastasis. After two courses without any major adverse effects, liver metastasis remarkably reduced on CT and MRI examination. We thus performed a liver resection, and pathological examination revealed a complete response in liver. Combination chemotherapy of 5-FU/LV and bevacizumab can be expected to provide safe and effective treatment for liver metastasis of colon cancer.
Authors
Shinnosuke Uegami, Yuji Imamura, Yutaka Daimaru, Atsushi Nakamitsu, Mohei Kouyama, Aki Kuwada, Kunio Toge, Hiroyuki Taogoshi, Satoshi Yokoyama, Yasuhiko Fukuda
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