Recommendations for diagnosis and management of multiple sclerosis.

Journal: Acta Clinica Croatica
Published:
Abstract

Multiple sclerosis (MS) is a chronic demyelinating neurologic disorder that mainly affects young individuals (aged 20 to 50 years). Approximately 85% of patients experience an initial course with relapses and remissions (relapsing-remitting multiple sclerosis). Guidelines for the management of MS should be focused on three main areas: (a) the diagnosis of MS; (b) treatment of relapses; and (c) long-term preventive treatment including clinical follow up, dose adjustment, drug switch, control of therapeutic efficacy, and disease progression. Diagnosis should be established according to clinical and paraclinical criteria. Discussion on therapeutic recommendations is focused on the disease-modifying agents in acute phases and drugs for long-term treatment and symptomatic treatment. Differential diagnoses must be taken into account on making the diagnosis of MS. Therefore, diagnosis of MS should be established on clinical and radiological diagnostic criteria, cerebrospinal fluid analysis and evoked potentials.

Authors
Vanja Kes, Iris Zavoreo, Vesna Serić, Vesna Solter, Marijan Cesarik, Sanja Hajnsek, Marija Pasić, Tereza Gabelić, Basić Silvio, Silva Butković, Ivo Lusić, Lidija Grbelja, Ante Vladić, Ivan Bielen, Igor Antoncić, Vida Demarin
Relevant Conditions

Multiple Sclerosis (MS)