Branch-selective allylic C-H carboxylation of terminal alkenes by Pd/sox catalyst.
Journal: Organic Letters
Published:
Abstract
A ligand-controlled branch-selective allylic C-H carboxylation through Pd catalysis is described. The developed catalytic system, which consists of Pd(OAc)2, sulfoxide-oxazoline (sox) as a ligand and benzoquinone as an oxidant, couples terminal alkenes and carboxylic acids to furnish the corresponding branched allylic esters with high regioselectivity.
Authors
Hiroki Kondo, Feng Yu, Junichiro Yamaguchi, Guosheng Liu, Kenichiro Itami