Simple alcohols promoted direct C-H arylation of unactivated arenes with aryl halides.
Journal: Chemical Communications (Cambridge, England)
Published:
Abstract
Simple and cheap alcohols can promote the direct arylation of unactivated arenes with aryl iodides and bromides in the presence of potassium tert-butoxide. This transition-metal-free aromatic C-H transformation offers a cheap and easy practical way to synthesize biaryls under mild conditions.