Simple alcohols promoted direct C-H arylation of unactivated arenes with aryl halides.

Journal: Chemical Communications (Cambridge, England)
Published:
Abstract

Simple and cheap alcohols can promote the direct arylation of unactivated arenes with aryl iodides and bromides in the presence of potassium tert-butoxide. This transition-metal-free aromatic C-H transformation offers a cheap and easy practical way to synthesize biaryls under mild conditions.

Authors
Wei Liu, Fei Tian, Xiaolei Wang, Hao Yu, Yanlan Bi