Nickel-catalyzed chelation-assisted direct arylation of unactivated C(sp3)-H bonds with aryl halides.
Journal: Chemical Communications (Cambridge, England)
Published:
Abstract
In this work, we have disclosed the nickel-catalyzed unactivated β-C(sp(3))-H bond arylation of aliphatic acid derivatives with aryl iodides/bromides via bidentate chelation-assistance of an 8-aminoquinoline moiety. These preliminary results indicate the intrinsic catalytic potential of nickel metal for unactivated C(sp(3))-H bond arylation.
Authors
Mingliang Li, Jiaxing Dong, Xiaolei Huang, Kaizhi Li, Qian Wu, Feijie Song, Jingsong You