AIDS-related primary CNS non-Hodgkin's lymphoma in a patient with previous Epstein-Barr virus panuveitis. A clinico-pathological report
Journal: Archivos De La Sociedad Espanola De Oftalmologia
Published:
Abstract
Methods: Patient with AIDS and Epstein-Barr virus (EBV) uveitis. The PCR of the aqueous and vitreous humor was positive for EBV, and DNA quantification was 56.602×10(6) copies/ml in the vitreous humor, 173,400 copies/ml in the peripheral blood, and negative in the cerebrospinal fluid (CSF). The patient developed a non-Hodgkin's lymphoma (NHL), diagnosed in the autopsy.
Conclusions: The EBV is a rare cause of uveitis and it may be necessary to perform a quantitative PCR to reach the diagnosis. High amounts of EBV DNA are associated with a greater incidence of NHL.
Authors
S Ruiz Bilbao, Hernández, S Gómez Sánchez, J Romeu, L Llobera L, C Carrato, R Anglada, A Sabala, L Matas
Relevant Conditions