Surgical indication for two cases of symptomatic Rathke's cleft cysts with spontaneous involution

In cases of symptomatic Rathke's cleft cysts with headache, visual disturbance, and endocrinopathy, we choose operations. But, the effects of operations are different according to the symptoms. Recently, there are some reports of Rathke's cleft cysts with spontaneous involution, and we need to reconsider the surgical indication for symptomatic Rathke's cleft cysts. We also had two cases of suspected Rathke's cleft cysts with spontaneous disappearance. Taking these experiences into account, we may spend time on detecting the operative indication for symptomatic Rathke's cleft cysts with the symptom such as headache. But, we should evaluate pituitary function by hormone-loading tests immediately to consider the operative indication for cases with symptoms such as endocrine dysfunction.