Image-enhanced endoscopy and magnifying endoscopy for esophageal cancer

Image diagnoses for esophageal cancer are progressing. With regard to endoscopic examination, chrome endoscopy using iodine have been performed so far to identify the range of lesion and to detect multiple primary cancers. In addition to that, endoscopic ultrasonography is used to diagnose the depth of tumor invasion and to identify lymph node metastasis. Recently, image-enhanced endoscopy (IEE) [e.g. Flexible spectral Imaging Color Enhancement (FICE), i-scan, Narrow Band Imaging (NBI), Autofluorescence imaging (AFI)] has developed. IEE is useful to detect superficial lesion, and is being utilized for diagnosing the tumor depth of invasion by using magnifying endoscopy( ME) together. In this literature, recent progress of endoscopic diagnosis, especially about IEE and ME, is reviewed. In addition to that, a way of endoscopic examination using IEE and ME is introduced.