Isolated acute dysphagia due to varicella-zoster virus.

Journal: Journal Of Clinical Virology : The Official Publication Of The Pan American Society For Clinical Virology
Published:
Abstract

We present a case of zoster sine herpete causing isolated acute dysphagia in an immunocompetent patient. The interest of this paper is the atypical presentation of varicella-zoster virus reactivation. A 77-year-old woman presented with a 3-day history of fever and worsening dysphagia for both liquid and solid foods. Cerebrospinal fluid examination revealed lymphocytic pleocytosis and PCR amplified varicella-zoster virus DNA with high antibody titers in both serum and cerebrospinal fluid. The panel was suggestive of a cranial neuritis due to varicella-zoster virus, involved cranial nerves, even in the absence of a cutaneous and mucosal rash. Varicella-zoster virus reactivation should be included in the differential diagnosis of isolated or multiple cranial nerve palsies, with or without zosteriform skin lesions. A prompt etiologic diagnosis can lead to early administration of antiviral therapy.

Authors
Vittorio Mantero, Andrea Rigamonti, Sergio Valentini, Anna Fiumani, Francesca Piamarta, Paolo Bonfanti, Andrea Salmaggi
Relevant Conditions

Swallowing Difficulty, Shingles