Diversity-oriented stereoselective synthesis of β,γ-disubstituted tert-homoallylic alcohols.

The successive treatment of β-(trimethylsilyl)allyl phenyl sulfides with titanocene(II)-1-butene complex and ketones produced tertiary γ-(trimethylsilyl)homoallylic alcohols with good anti-selectivity, which reacted with a variety of organic halides in the presence of copper(I) tert-butoxide to afford the cross-coupling products, γ-substituted homoallylic alcohols.