A case of highly advanced gastric cancer with peritoneal dissemination -- a histological CR to S-1 and CDDP combination chemotherapy

A 64-year-old man with type 3 advanced gastric cancer was referred to our hospital. Abdominal computed tomography (CT)showed thickening of the gastric wall and lymph node metastasis near the stomach, and laparoscopy revealed peritoneal dissemination. After 6 courses of CDDP therapy, lymph node metastasis was no longer detectable on CT scans. A second laparoscopy showed no peritoneal dissemination; therefore, distal partial gastrectomy with D2 lymph node dissection was performed. Histological examination showed no tumor cells in the gastric primary lesion, no metastatic lymph nodes, and no disseminated peritoneal nodules, suggesting pathological complete remission.