Retinoblastoma in oculocutaneous albinism.

Journal: Retinal Cases & Brief Reports
Published:
Abstract

Objective: To report a case of retinoblastoma in a child with oculocutaneous albinism (OCA).

Methods: A 24-month-old girl with classic features of OCA developed leukocoria in the left eye.

Results: The patient was found to have an endophytic retinoblastoma and an exophytic retinoblastoma, with a total retinal detachment and neovascularization of the iris. Enucle-ation was performed, and histopathology confirmed massive retinoblastoma with optic nerve involvement to the posterior margin of the lamina cribrosa but no choroidal invasion.

Conclusions: Although rare, retinoblastoma can occur in children with OCA.

Authors
Fariba Ghassemi, Carol Shields, Cesare Pirondini, Ralph Eagle, Jerry Shields