The impact of genomics on public health practice.

Background: Genomic science is developing rapidly, and engagement of public health professionals will be necessary to appraise new technologies and use them effectively.

Methods: We use established domains of public health and draw on the literature and expert knowledge to illustrate how genomic technologies give rise to new applications.

Results: Genomic technologies are useful in rare inherited disease, including population screening programmes, in health care and for surveillance, diagnosis and treatment of infectious disease. Results: It is less clear when and how genetic susceptibility testing will be used for common chronic disease prevention or protection from environmental hazards.

Conclusions: Developments in public health practice will be necessary to ensure rapid and effective implementation of genomic science. Conclusions: Public health researchers should address how to accelerate the implementation of genomics for health benefit in developed and developing countries.