Silver(I)-catalyzed ring-contractive rearrangement: a new entry to 5-alkylidene-2-cyclopentenones.
Journal: Organic Letters
Published:
Abstract
A novel silver(I)-catalyzed ring-contractive rearrangement of 5-substituted 6-diazo-2-cyclohexenones has been developed, providing a new and efficient access to 5-alkylidene-2-cyclopentenones. The AgOTf-catalyzed reaction proceeds through metal-carbenoid formation followed by endocyclic allyl [1,2] migration with excellent stereoselectivity and broad substrate scope.
Authors
Liang Zhao, Jinlian Wang, Hongyan Zheng, Yun Li, Ke Yang, Bin Cheng, Xiaojie Jin, Xiaojun Yao, Hongbin Zhai