Intermolecular gold(I)-catalyzed cyclization of furans with alkynes: formation of phenols and indenes.
Journal: Chemistry (Weinheim An Der Bergstrasse, Germany)
Published:
Abstract
A heart of gold: Phenols can be obtained by the intermolecular reaction of furans with alkynes by using [AuIPr](+)A(-) catalysts (see scheme). 1,3-Diphenylisobenzofuran also reacts via a cyclopropyl gold carbene to selectively form 2,3-disubstituted indenes. (IPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene; A = anion.).
Authors
Núria Huguet, David Lebœuf, Antonio Echavarren