Immune mediated crescentic MPGN secondary to HBV infection: A rare presentation for a common infection.
Journal: The Australasian Medical Journal
Published:
Abstract
Hepatitis B virus (HBV) infection presenting as crescentic glomerulonephritis in the absence of cryoglobulinemia is an extremely rare phenomenon. We report a case of a 44-year-old male with HBV infection, who underwent kidney biopsy for rapidly progressive renal failure and nephrotic range proteinuria. Histopathological evaluation of the kidney biopsy was consistent with immune complex mediated crescentic membranoproliferative glomerulonephritis (MPGN). The patient achieved complete renal and virological remission with steroids, plasmapheresis and antiviral therapy. This case report summarises the importance of early initiation of immunosuppression and plasmapheresis under antiviral coverage for improved clinical outcomes.
Authors
Aswani Mareddy, Dharshan Rangaswamy, Mahesha Vankalakunti, Ravindra Attur, Shankar Nagaraju, Neeraja Koti
Relevant Conditions