Factors related to anxiety and depression in patients undergoing adrenalectomy in 220 Chinese people.

Objective: The aim of this study was to evaluate the factors related to anxiety and depression in patients undergoing adrenalectomy.

Methods: From October 2011 to October 2014, 220 consecutive inpatients undergoing adrenalectomy were enrolled in this study. Documented informed consent for the study was obtained from each subject. All subjects completed a detailed questionnaires for information of sociodemographics, the Zung self-rating anxiety scale (SAS), the Zung self-rating depression scale (SDS) before operations, and three days after operations.

Results: Univariate analysis showed that preoperative SAS and SDS scores were positively related to age (r=0.280, r=0.322, respectively, both P<0.001). And a high degree of preoperative anxiety or depression was correlated with their low level of educational status, and with the occurrence of religious faith. The same negative relation was found between SAS/SDS and level of educational status after operation. Multiple regression analysis revealed that age and level of educational status were related to preoperative SAS (β=0.072, P<0.05 and β=-0.838, P<0.05, respectively). The occurrence of laparoscopic operation was negatively related to preoperative SDS (β=-1.932, P<0.05). Age, gender and other diseases were related to postoperative SAS. And other diseases were also related to postoperative SDS.

Conclusions: The present study suggested that age, gender, other diseases, level of educational status, operation method were associated with anxiety or depression before or after operations. Individual traits should be taken into account when we intervene to treat anxiety and depression in patients undergoing adrenalectomy.