Interleukin-6 concentrations in the vitreous body of patients with retinal detachment.
Journal: Archivos De La Sociedad Espanola De Oftalmologia
Published:
Abstract
Objective: To measure interleuquin-6 (IL-6) levels in the vitreous body of patients with retinal detachment (RD).
Methods: Undiluted vitreous samples were obtained from 40 patients with no history of prior vitreous or intraocular surgery. Patients were divided into two groups: A (n=20) patients with RD and B (n=20) patients with pre-retinal macular membranes and macular holes. IL-6 was determined using radioimmunoassay.
Results: IL-6 vitreous concentration in group A was 122.4+-16pg/mL (range 91.5-620) and in group B was 46+/-23pg/mL (range 3-150) (p <.001).
Conclusions: These results show that the concentration of IL-6 in the vitreous body was significantly higher in patients with RD than in the control group.
Authors
V Asensio Sánchez, J Collazos, M Cantón
Relevant Conditions