A rapid construction of the ABC tricyclic skeleton of malabanone A.
Journal: Organic & Biomolecular Chemistry
Published:
Abstract
The construction of the ABC tricyclic skeleton of malabanone A with the required 4 stereocenters was accomplished in a concise route starting from R-carvone. The synthesis featured an intramolecular [3 + 2] cycloaddition reaction to assemble its A ring and an intramolecular Diels-Alder reaction to construct its C ring.
Authors
Tao Li, Guangmiao Wu, Shangbiao Feng, Zemin Wang, Xingang Xie, Xuegong She