Palladium-catalyzed trisallylation of benzoxazoles and 2-aryl-1,3,4-oxadiazoles with alkyne.
Journal: Chemical Communications (Cambridge, England)
Published:
Abstract
A Pd-catalyzed direct C-H trisallylation of azoles with alkyne has been described. A consecutive C(sp2)-H allylation/olefin isomerization/double C(sp3)-H allylation of azoles and alkyne via a palladium catalysis system proceeds efficiently to afford the corresponding C2-alkenylated azoles containing an all quaternary carbon center.
Authors
Jun Zheng, Fereshteh Hosseini Eshbala, Ya-xi Dong, Bernhard Breit