Manganese(I)-Catalyzed C-H Activation/Diels-Alder/retro-Diels-Alder Domino Alkyne Annulation featuring Transformable Pyridines.
Journal: Angewandte Chemie (International Ed. In English)
Published:
Abstract
Complexity-increasing Domino reactions comprising C-H allenylation, a Diels-Alder reaction, and a retro-Diels-Alder reaction were realized by a versatile catalyst derived from earth-abundant, non-toxic manganese. The C-H activation/Diels-Alder/retro-Diels-Alder alkyne annulation sequence provided step-economical access to valuable indolone alkaloid derivatives through a facile organometallic C-H activation manifold with transformable pyridines.
Authors
Cuiju Zhu, Rositha Kuniyil, Lutz Ackermann