Effects of multiple transmission pathways on Zika dynamics.

Although the Zika virus is transmitted to humans primarily through the bite of infected female Aedes aegypti mosquitoes, it can also be sexually and vertically transmitted within both populations. In this study, we develop a new mathematical model of the Zika virus which incorporates sexual transmission in humans and mosquitos, vertical transmission in mosquitos, and mosquito to human transmission through bites. Analysis of this deterministic model shows that the secondary transmission routes of Zika increase the basic reproductive number (