Single-shot imaging of microscopic dynamic scenes at 5 THz frame rates by time and spatial frequency multiplexing.

Femtosecond-scale ultrafast imaging is an essential tool for visualizing ultrafast dynamics in many scientific fields. We present a single-shot ultrafast microscopy that can capture more than a dozen frames at a time with the frame rate of 5 THz. We combine a spatial light modulator and a custom-made echelon for efficiently generating a large number of reference pulses with designed time delays and propagation angles. The single-shot recording of the interference image between these reference pulses with a sample pulse allows us to retrieve the stroboscopic images of the dynamic scene at the timing of the reference pulses. We demonstrated the recording of 14 temporal snapshots at a time, which is the largest to date, with the optimal temporal resolution set by the laser output pulse. This will have profound impacts on uncovering the interesting spatio-temporal dynamics yet to be explored.