Rtpca: an R package for differential thermal proximity coaggregation analysis.

Summary: Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages. Availability and implementation: Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca). Supplementary information: Supplementary data are available at Bioinformatics online.