Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system.
Journal: Talanta
Published:
Abstract
Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
Authors
Antonio Marín Romero, Mavys Tabraue Chávez, James Dear, Rosario Sánchez Martín, Hugh Ilyine, Juan Guardia Monteagudo, Mario Fara, Francisco López Delgado, Juan Díaz Mochón, Salvatore Pernagallo