Cryptic transmission of SARS-CoV-2 in Washington state.
Journal: Science (New York, N.Y.)
Published:
Abstract
After its emergence in Wuhan, China, in late November or early December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly spread globally. Genome sequencing of SARS-CoV-2 allows the reconstruction of its transmission history, although this is contingent on sampling. We analyzed 453 SARS-CoV-2 genomes collected between 20 February and 15 March 2020 from infected patients in Washington state in the United States. We find that most SARS-CoV-2 infections sampled during this time derive from a single introduction in late January or early February 2020, which subsequently spread locally before active community surveillance was implemented.
Authors
Trevor Bedford, Alexander Greninger, Pavitra Roychoudhury, Lea Starita, Michael Famulare, Meei-li Huang, Arun Nalla, Gregory Pepper, Adam Reinhardt, Hong Xie, Lasata Shrestha, Truong Nguyen, Amanda Adler, Elisabeth Brandstetter, Shari Cho, Danielle Giroux, Peter Han, Kairsten Fay, Chris Frazar, Misja Ilcisin, Kirsten Lacombe, Jover Lee, Anahita Kiavand, Matthew Richardson, Thomas Sibley, Melissa Truong, Caitlin Wolf, Deborah Nickerson, Mark Rieder, Janet Englund, Emma Hodcroft, John Huddleston, Louise Moncla, Nicola Müller, Richard Neher, Xianding Deng, Wei Gu, Scot Federman, Charles Chiu, Jeffrey Duchin, Romesh Gautom, Geoff Melly, Brian Hiatt, Philip Dykema, Scott Lindquist, Krista Queen, Ying Tao, Anna Uehara, Suxiang Tong, Duncan Maccannell, Gregory Armstrong, Geoffrey Baird, Helen Chu, Jay Shendure, Keith Jerome
Relevant Conditions