Benzoic Acid-Promoted C2-H Borylation of Indoles with Pinacolborane.
Journal: Organic Letters
Published:
Abstract
A benzoic acid-promoted C2-H borylation of indoles with pinacolborane to afford C2-borylated indoles is developed. Preliminary mechanistic studies indicate BH3-related borane species formed via the decomposition of pinacolborane to be the probable catalyst. This transformation provides a prompt route toward the synthesis of diverse C2-functionalized indoles.
Authors
Youliang Zou, Binfeng Zhang, Li Wang, Hua Zhang