Evaluation of Cortactin and HS1 Genes Expression: New Players in Adult B-Cell Acute Lymphoblastic leukemia.

Journal: Asian Pacific Journal Of Cancer Prevention : APJCP
Published:
Abstract

Objective: This study aimed to assess the prognostic value of cortactin and HS1 genes expression in adult B-cell acute lymphoblastic leukemia.

Methods: The study included a cohort of 74 adult B-ALL patients and 76 controls. Cortactin and HS1 genes expression were quantified by real time PCR.

Results: The expression of cortactin and HS1 were significantly higher in B-ALL patients at diagnosis as compared to post induction levels (p.

Authors
Salah Aref, Mohamed Al Agdar, Ahmed Ramez, Tarek Abou Zeid, Mohamed Sabry, Nada Khaled