Nitrogen bridgehead compounds. Part 7: Synthesis of anti-atherosclerotic pyrido[1,2-a]pyrimidines.
Journal: Arzneimittel-Forschung
Published:
Abstract
The synthesis of 9-substituted-pyrido[1,2-a]pyrimidines are described. The new compounds exhibit antiatherosclerotic effects. The 3-ethoxycarbonyl-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-9-acetic acid (Chinoin-123) has the most favourable effects.
Authors
I Hermecz, Z Mészáros, L Vasvári Debreczy, A Horváth, S Virág, J Sipos