Gingival hyperplasia in a heart transplant patient treated with cyclosporin A and nifedipine

Cyclosporin-A and Nifedipine-induced gingival enlargement have been reported to have similar clinical and histopathological features as phenytoin. The present case report describes the clinical course and treatment of a young heart-transplant patient who developed gingival hyperplasia under both Nifedipine and Cyclosporin-A. After withdrawing Nifedipine from his daily medication and a second step of surgical excision, the patient presents no recurrence of gingival enlargement, 6 months post-treatment despite his Cyclosporin-A regimen and poor oral hygiene.